NEWS BRIEF

Molecular Imaging today
GE HealthCare is transforming molecular imaging with a comprehensive, end-to-end platform that supports personalized care across the patient journey. For over 25 years, the company has been a pioneer in PET/CT innovation, and its comprehensive portfolio spans cyclotrons, chemistry synthesis, pharmaceutical diagnostics, PET/MR, SPECT/CT, and advanced digital solutions. These technologies help enable precision care and theranostics, improve workflow efficiency, and enhance diagnostic confidence across care areas – namely oncology, neurology, and cardiology. GE HealthCare continues to support and drive innovation to meet the evolving needs of molecular imaging departments and reinforce its role as a trusted partner in advancing patient-centered care.

On the show floor at #RSNA25, GE HealthCare will showcase Omni Legend mobile, a portable, all-in-one PET/CT solution that further extends Omni Legend’s capabilities to regional or local scan centers to help increase access to advanced imaging while helping reduce travel burdens, especially for more vulnerable or remote patient communities.

Omni Legend boasts more than two times the sensitivity of prior digital scanners , enabling faster scan times and impressive small lesion detectability. Combined with Precision DL, GE HealthCare’s revolutionary deep learning-based image processing software provides the image quality performance benefits typically associated with hardware-based ToF reconstruction, including improved contrast-to-noise ratio, contrast recovery, and quantitative accuracy.

Altogether, Omni Legend’s ultra-high sensitivity, third generation digital detector technology marks a new era for PET/CT performance, transitioning from ToF technology to the next generation of PET/CT performance and enabling clinicians to decode coincidence events at exceptionally fine resolutions for informed diagnoses and treatment planning across care areas.

Omni 128cm total body PET/CT
GE HealthCare has announced CE Mark for its next-generation Omni 128cm total body positron emission tomography / computed tomography (PET/CT) system , a major milestone in its mission to advance precision care. Designed to advance cancer care, this innovative system is designed with 128cm Axial Field of View (AFOV) to accommodate head to thigh imaging in a single bed position for a wide range of patients, helping accelerate scan time and streamline workflow with intuitive artificial intelligence solutions to promote great clinical and operational efficiency. The system also enables ultra-low dose scans, multi-organ dynamic imaging, and imaging of slow-decaying, low-activity tracers, with the goal to enhance both clinical practice and research, while enabling improved operational efficiency across healthcare systems.

In addition, the Omni 128cm PET/CT system aims to support advanced research applications – from developing new clinical pathways and novel PET tracers, to evaluating emerging theranostic agents – accelerating innovation from bench to bedside. The company continues to drive a connected healthcare transformation, delivering integrated solutions that empower clinicians and help improve patient outcomes worldwide.

Read the full press release for more details.

Digital 4D SPECT/CT: StarGuide™ GX
GE HealthCare announces CE Mark for StarGuide™ GX , a new digital 4D SPECT/CT system designed with excellent precision, clinical efficiency, and impressive versatility. StarGuide GX empowers personalized care and research innovation as nuclear medicine expands into new applications.

StarGuide GX comes at a pivotal time for the field of nuclear medicine. As complex diseases such as cancer, Alzheimer’s, and cardiovascular disease become increasingly prevalent, the demand for precision diagnostics and targeted therapies is accelerating. StarGuide GX helps meet this need head-on, enabling clinicians to break free from energy-range limitations and image tracers with exceptional clarity. With growing demand for digital SPECT/CT – partially driven by the rise of theranostics – GE HealthCare’s innovation arrives as departments seek all-in-one, scalable solutions to help manage increasing patient volumes and complex treatment protocols.

Intentionally designed for versatility, StarGuide GX represents an all-in-one system virtually capable of imaging all energy levels for general-purpose SPECT imaging – as well as acquisition of investigational alpha therapies such as Actinium-225 – with excellent image quality, optimizing it for exploring imaging of emerging therapies. The system’s ability to image closer to organs helps deliver excellent resolution and quantitation, both of which are important for treatment planning and monitoring. This enables clinicians to image tracers with exceptional clarity, with impressive workflow efficiency.

GE HealthCare continues to deliver on its promise to transform the future of nuclear medicine – helping empower clinicians, improve outcomes, and advance precision health for patients worldwide.

Read the full press release for more details.

Media contact
Margaret Steinhafel
Global Communications Director
Molecular Imaging & Computed Tomography
margaret.steinhafel@gehealthcare.com
M: +1 608 381 8829

1. Omni Legend 32 cm has up to 2.2x increase in system sensitivity as compared to Discovery MI 25 cm. Measurement follows NEMA NU 2-2018.
2. Up to 53% reduction of PET scan time on Omni Legend 32 cm compared to Discovery MI 25 cm, as demonstrated in phantom testing.
3. Omni Legend 32 cm increases small lesion detectability 16% on average and up to 20%, as compared to Discovery MI 25 cm with matched scan time/injected dose, as demonstrated in phantom testing using a model observer with 4 mm lesions; average of different reconstruction methods.
4. Precision DL with Omni Legend 32cm data improves Contrast Recovery (CR) by 11% on average and Contrast-to-Noise Ratio (CNR) by average of 23% as compared to non-ToF reconstruction. CR and CNR demonstrated using clinical data with inserted lesions of known size, location, and contrast. Using data from Omni Legend 32 cm, CR and CNR were measured using High Precision DL and QCHD.
5. Precision DL with Omni Legend 32cm improves feature quantitation accuracy by 14% as compared to Discovery MI with ToF reconstruction, at comparable noise level. Quantitation accuracy demonstrated using clinical data with inserted lesions of known size, location, and contrast (ground truth). Feature SUVmean from Omni Legend 32 cm with High Precision DL compared to SUVmean from Discovery MI 25 cm with QCFX.
6. The Omni 128cm AFOV total body PET/CT is CE marked. Available for sale in EU member state countries. Not approved or cleared by the U.S. FDA. Not available for sale in the United States and other non-EU countries.
7. StarGuide Next Gen is CE marked. Available for sale in EU member state countries. Not approved or cleared by the U.S. FDA. Not available for sale in the United States and other non-EU member state countries.