PET Radiochemistry Systems

True discovery is made possible because of the biochemical processes that tracers allow us to see. As a result, the research and development of new tracers is just as important as innovations in the technology used to image them. This requires a commitment not only to the efficient production of important tracers like FDG, but also to the development of new tracers that will lead to new avenues of true discovery.

With over 20 years of expertise in PET diagnostic drug development and production as our guide, we developed a portfolio of chemistry systems designed to be highly productive and reliable for your everyday tracer needs, as well as customizable and flexible for your research needs.

FASTlab™ 2 is a multi-tracer platform featuring an innovative, integrated-cassette-based design that gives it a unique, plug-and-play functionality. This one-of-a-kind design improves usability, increases efficiency and is economical for wide-spread tracer distribution. In fact, it is our platform of choice for developing and producing our own proprietary PET tracers. This innovative and flexible platform is also the platform of choice for developing not just 18F labelled tracers but beyond to include radio-metal labelled tracers (61Cu, 64Cu, 68Ga, 89Zr), and the list continues to grow.

For facilities interested in developing novel tracers, the TRACERlab™ FX2 Series of chemistry systems provide the customizable functionality needed to automate different chemistry pathways beyond a linear cassette fluid path or using reagents or solvents at higher temperatures.

With this comprehensive collection of chemistry systems, you can efficiently produce the tracers necessary for true discovery today, or research future tracers that will be needed for tomorrow.

The first step in every journey of discovery with PET imaging begins with tracer production. Every tracer that you produce and deliver can lead to a crucial moment of discovery; every tracer has the potential to change lives. We understand that, in order to succeed as a profitable world-class tracer center, providing a cost-effective service while delivering outstanding quality is key. To achieve this, your PET center requires efficient, predictable tracer output.

The FASTlab 2 New Edition

• enables reliable quality and yield even at high-activity: proven 78% yield (EOS) from 550+ FDG phosphate runs, standard deviation of +/- 3% points.
• is proven for heavy duty production up to 30 Ci input activity, enabled by radiation hardening redesign of the electronics
• is powered by our customers’ achievements with 2600+ radiochemistry systems including 740+ FASTlabs worldwide
• brings high reliability proven by 99.6% system uptime and
• introduces integrated cyber security software enabled by safety analysis of the software, role-based user access levels and a hardened operating system

What sets FASTlab 2 New Edition apart from all other radiochemistry systems is its unique integrated cassette-based design together with GMP quality components (e.g. vials) which enable and ease the regulatory reliability & compliance in tracer production. Pre-measured quantities of every chemical and component needed for the synthesis of a radiopharmaceutical are contained in a single cassette. That means it only takes two simple steps to start producing virtually any clinical tracer you need. All you have to do is drop in a pre-loaded cassette and the system is ready for processing.

This unique, cassette-based system not only simplifies this step of tracer production, it also makes it more reliable and secure compared to other methods. Our cassettes are manufactured in a controlled environment, pre-loaded with reagents produced under cGMP standards, barcoded for automatic identification and sealed shut. They are also disposable, so when a run is complete, each component that comes into contact with the chemical is replaced to ensure clean operation.

FASTlab 2 is designed for easy, confident production of a broad spectrum of PET tracers. It enables automated synthesis of FDG and other 18F-based PET tracers with high output and uptime. Two synthesizers can be stacked into a single hot cell, giving you greater output and saving valuable lab space. With our FDG Duo cassette, you can perform up to four FDG citrate runs without opening the hot cell door.

In addition, FASTlab 2 Developer gives you even greater flexibility by enabling you to develop your own tracers and then allowing you to produce them using the cassette system.

Meet current and future demands with a scalable solution.

FASTlab 2 New Edition enables you to access new tracers and meet variable demand.

From easy GMP production of key tracers to implementing tracers developed in-house or by partners. FASTlab 2 New Edition also provides an open platform to produce innovative tracers for research, whether 18F labelled or radio-metal based e.g., 61Cu, 64Cu, 68Ga,89Zr.