Theranostics

Accurate dosimetry helps evaluate and monitor the dose absorbed by sensitive organs as well as lesions. The dosimetry process can be challenging, as it requires the processing of multiple studies including organ and lesion segmentation, as well as the use of laborious and tedious methods for dose assessment.

Designed for efficient dosimetry and quantitation, Q.Thera AI is GE HealthCare’s solution for Theranostics treatment monitoring empowered by AI. Q.Thera AI segments lesion volumes and automatically segment patient organs, including through the use of AI. It also automatically quantifies and calculates the percent of injected dose and absorbed dose per organ and lesion.

This workflow is designed to enable a reduction in time⁶ from data loading to dose calculation and the number of clicks to achieve dose calculation, enhancing workflow.

GE HealthCare’s end-to-end solution for advanced segmentation and quantitation is empowered by AI. It offers advanced segmentation and quantitation capabilities for SPECT/CT and PET/CT data without impeding workflow for both baseline and longitudinal studies. Offering efficient reconstruction with attenuation, scatter, and resolution compensation, it is a simple, automatic method for liver, kidney, bone, lung, soft tissue, and lesions segmentation—all important for Theranostics treatment evaluation and monitoring. Quantitative monitoring enables evaluating the dose absorbed in tumors, helping in personalized response assessment. It also provides information on tumor burden reduction on each cycle.

Selective internal radiation therapy (SIRT) requires information on patient suitability for treatment and preliminary dose calculation. Liver segmentation is time consuming, tedious, and highly operator dependent, and manual shunt calculation on planar images is time consuming and user dependent. Determining a recommended dose usually requires multiple tools.

Q.Liver is GE HealthCare’s streamlined solution to facilitate SIRT treatment planning. It is designed for 3D-dosimetry segmentation, enabling the processing and quantification of liver SPECT, PET, and CT segmentation with tools to calculate a therapeutic dose for SIRT treatments. Time to achieve dose calculation and liver segmentation is reduced,⁷ as well as is the number⁸ of clicks needed to achieve dose calculation.