TRACERlab FX MeI and FX M Chemistry Synthesizers|Flexible|GEHC UK

TRACERcenter* offers easy-to-use TRACERlab* solutions that deliver high 11C-based tracer productivity. TRACERlab systems are also scalable and flexible.

TRACERlab FX2 MeI
The TRACERlab FX2 MeI, evolution of the TRACERlab FX MeI, is a fully automated system for easy and efficient production of [¹¹C] methyl iodide or [¹¹C] methyl triflate, both precursors for many important [¹¹C] tracers.

TRACERlab FX2 MeI combines flexibility and productivity. It provides a patented gas phase [¹¹C] methyl iodide production method via direct reaction of Iodine with [¹¹C] methane. [¹¹C] methane can either be supplied from a [¹¹C] methane target or in case a [¹¹C]CO₂ target is used, the integrated conversion step of [¹¹C]CO₂ to [¹¹C] methane can be utilized.

More than 50 tracers have been produced and published using TRACERlab FX C Pro and the couple TRACERlab FX2 MeI / TRACERlab FX2 M can run all these synthesis methods too.

TRACERlab FX2 M
The TRACERlab FX2 M, evolution of the TRACERlab FX M, is a fully automated system for easy and efficient production of [¹¹C] tracers starting with a suitable [¹¹C] precursor like [¹¹C] methyl iodide or [¹¹C] methyl triflate. A typical synthesis system combines between one and four TRACERlab FX2 M modules with one TRACERlab FX2 MeI module that delivers the [¹¹C] precursor.

TRACERlab FX2 M combines flexibility and productivity. It allows to produce [¹¹C] tracers starting with [¹¹C] methyl iodide or [¹¹C] methyl triflate.

More than 50 tracers have been produced and published using TRACERlab FX C Pro and the couple TRACERlab FX2 MeI / TRACERlab FX2 M can run all these synthesis methods too.

High Performance and Reliability

TRACERlab FX2 MeI and FX2 M are designed to help you:

• Achieve high yield
• Increase productivity with easy-to-use operation
• Improve cost-efficiency by using just one FX2 MeI to feed up to four FX2 M modules
• Formulate final solution
• Minimize radioactivity
• Program easily for customization and flexibility
• Save time by modifying processes with just a few keystrokes
• Reduce need for reagents; FX2 MeI reagents last six to ten runs
• Perform back-to-back [ ¹¹ C]-methyl iodide runs
• Transfer precursor automatically from FX2 MeI to FX2 M

TRACERlab FX2 MeI:

The TRACERlab FX2 MeI integrates all the necessary steps for the production of [¹¹C] methyl iodide or [¹¹C] methyl triflate.

• Trapping of [ ¹¹ C]-carbon dioxide or [ ¹¹ C]-methane,
• Patented gas-phase synthesis of [ ¹¹ C]methyl iodide and [ ¹¹ C] methyl triflate with high specific activity,
• Conversion to methyl iodide,
• Optional conversion to methyl triflate,
• Optional [ ¹¹ C]-carbon dioxide concentration for further rapid processing of carboxylation reactions,
• Gas system sealed against room air.

All production steps are fully automated.

For production of a final tracer up to four TRACERlab FX2 M can be connected to the TRACERlab FX2 MeI. Also other methylation units like TRACERlab FX M can be connected.

TRACERlab FX2 M:

The TRACERlab FX2 M integrates all the necessary steps for the production of [¹¹C] tracers:

• Labeling reactor with heating, cooling and stirring features
• Build-in semipreparative HPLC purification
• Build-in formulation of the final tracer
• Gas and liquid system sealed against room air

All production steps are fully automated.

The semi-preparative radio-HPLC system comprises an injection valve, a semi-preparative HPLC column, a radioactivity flow-through detector, an UV detector and a fraction collector valve to isolate the final tracer.

TRACERlab FX2 MeI:

^{A Using purifiers for target gases input}

^{B Indicative values only, valid in combination with GE PETtrace cyclotron, not suitable for acceptance}

^{C At 75 GBq (2 Ci) [11C]CO2.}

System Characteristics

TRACERlab FX2 M:

System Characteristics