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Histologic analysis remains the primary mode of definitive diagnosis for a patient with suspected lymphoma.3 Although CT, MRI and PET/CT are complimentary tools for the non-invasive assessment of splenic involvement in various hematological malignancies.3

References:

3. Spleen in hematological malignancies: spectrum of imaging findings. S S Saboo, DNB, FRCR,1 K M Krajewski, MD,1 K N O'Regan, MD,1 A Giardino, MD,1 J R Brown, MD,2 N Ramaiya, MD,1 and J P Jagannathan, MD1. Br J Radiol. 2012 Jan; 85(1009): 81–92.

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