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Our fully integrated PET/MR system combines TOF, quantitative accuracy and high sensitivity with our innovative Q.Clear reconstruction.
Signal
A new era in personalized imaging with quantitative PET/MR
When we first introduced Time-of-Flight (TOF) technology on a fully integrated PET/MR system, we said it would be revolutionary. We delivered on that promise and now we are taking it even further.
Introducing SIGNA™ PET/MR with QuantWorks. Built with pioneering TOF and integrated with a 3.0T MR, its impressive quantitative accuracy and high count rate combined with innovative Q.Clear reconstruction delivers 2x improvement in image quality. In addition, SIGNA PET/MR with QuantWorks includes a comprehensive suite of applications and flexible research tools to pursue ideas that could influence the future of medicine.
SIGNA PET/MR with QuantWorks is not CE-marked and not commercially available in all regions.
Customer Testimonials
Mark Lubberink, PhD
Uppsala University Hospital, Svezia
Mark Lubberink, PhD, is a Professor of Molecular Imaging at Uppsala University and Senior Medical Physicist at the Uppsala University Hospital in the Nuclear Medicine & PET, Department of Surgical Sciences. He received his PhD in Medical Radiation Physics at Uppsala University. Dr. Lubberink’s research focuses on PET/MR, PET/CT and the many tracers produced at his institution.
Peder Larson, PhD
University of California - San Francisco
Peder Larson, PhD, is an Associate Professor in Residence and a Principal Investigator in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco (UCSF). Dr. Larson received his PhD in Electrical Engineering from Stanford University in 2007 followed by a Postdoctoral Fellowship in 2011. Since then, he has been running a research group at UCSF focused on magnetic resonance imaging (MRI) technology developments for improving cancer assessment.
Irene Burger, MD
Ospedale universitario di Zurigo, Svizzera
Irene Burger, MD, obtained her medical degree from the University of Zurich and is a board-certified radiologist and nuclear medicine physician at the University Hospital of Zurich in Switzerland. She has led the PET/CT center at the University Hospital of Zurich with emphasis on hybrid imaging in urogenital oncology since July 2014. She received venia legendi for radiology and nuclear medicine from the University of Zurich in 2015.
Georges El Fakhri, PhD
Georges El Fakhri, PhD, is a Professor of Radiology at Harvard Medical School (HMS) and the founding Director of the Endowed Gordon Center for Medical Imaging at Massachusetts General Hospital. He is also Co-director of the Division of Nuclear Medicine and Molecular Imaging. Dr. El Fakhri is an internationally recognized expert in quantitative molecular imaging (SPECT, PET-CT, and PET/MR) and has authored or co-authored over 200 papers and mentored over 90 students, post-docs and faculty.
Embrace
1. Light Tight RF Shield with copper coating
2. Lutetium Based Scintillator (LBS) crystal array with light and Enhanced Spectral Reflectors (ESR)
3.SiPM - Silicon PhotoMultiplier with circuit boards/ASICS
4. Thermal coupling gasket
5. Aluminum mounting plate
The full diagnostic potential of high sensitivity and TOF
SIGNA PET/MR with QuantWorks is built with proprietary Silicon PhotoMultiplier (SiPM) detectors and the exceptional sensitivity of 25 mm deep Lutetium-based crystals. The result is a fully integrated PET/MR with high sensitivity and TOF capability.
In addition, our innovative Q.Clear reconstruction leverages the excellent signal-to-noise ratio (SNR) enabled by TOF. And our Zero Echo Time (ZTE) MR substitutes X-ray based attenuation correction with ionizing-radiation-free MR in the head. This combination of improvements to image quality and quantitation accuracy enables you to embrace the full potential of PET/MR.
Establish
Trust with consistently accurate results.
When you can trust the accuracy of each result, quantitation takes on a whole new meaning.
SIGNA PET/MR with QuantWorks combines the clarity of our TOF technology with the consistency of Q.Clear. Using innovative reconstruction, Q.Clear incorporates prior knowledge about image quality into reconstructed images to decrease noise while providing quantitation accuracy and significantly improving image quality. In addition, SIGNA PET/MR with QuantWorks includes the most comprehensive motion correction package in the industry to reduce the effects of involuntary and physiological motion. And our ZTE MR, a true ZTE imaging technique, can ‘see’ bone for an ionizing-radiation-free attenuation correction method with MR.
This exclusive combination of TOF technology and Q.Clear provides you with another tool you can rely on to confidently guide the decisions that impact patient care.
Q.Clear
Q.Clear incorporates prior knowledge about image quality into the reconstructed image to decrease noise while providing quantitation accuracy and significantly improved image quality.
ZTE MR
ZTE MR replaces the X-ray based gold standard for attenuation correction with this accurate, personalized ionizing-radiation-free MR technique. Based on the high stability of SIGNA PET/MR with QuantWorks’ hardware, our ZTE MR is more reliable and faster than Ultra Short Echo (UTE) and improves image quality.
Comprehensive Motion Correction Solutions
Solutions to reduce involuntary and physiological movement with an extensive selection of motion correction applications for PET and MR, including PROPELLER, PROMO and Pencil Beam Navigator.
SIGNA™Works
The new standard is extraordinary
Our new SIGNA™Works applications portfolio redefines productivity and improves security across the breadth of our core imaging techniques. SIGNA PET/MR with QuantWorks comes preloaded with the standard applications portfolio of SIGNA™Works as a fully integrated package. This extensive library of high quality and efficient imaging techniques enables you to achieve the outcomes you desire across your entire practice.
SIGNA™Works’ advanced applications include HyperWorks, ViosWorks, ImageWorks and SilentWorks, which further advance diagnostics and accelerate throughput while simultaneously improving patient outcomes and your ROI.
Not only is SIGNA™Works upgradeable, it can be further customized, so you have the flexibility to add applications to suit the needs of your practice.
Energize
Phenomenal exams to meet your clinical needs
The SIGNA™Works standard applications portfolio contains imaging solutions that cover a wide variety of contrasts, 2D and 3D volumetric data, including motion correction capabilities. SIGNA™Works provides all of the tools you need to complete a clinical exam.
Clinical Gallery - Standard & Elective
Open New avenues of discovery
Explore all that PET/MR is capable of by using SIGNA PET/MR with QuantWorks’ extensive offering of research tools.
SIGNA PET/MR with QuantWorks has the tools you need to discover disease-specific tracers and develop new protocols. You can use PET/MR simultaneously with MR multinuclear spectroscopy as an in-vivo laboratory to study fast biochemical processes. In addition, PET ToolBox and Orchestra Software Development Kit give you offline access to our image reconstruction environments for PET and MR making it faster and easier to work on your own reconstruction ideas.
SIGNA PET/MR with QuantWorks provides the tools you need to push the boundaries of its innovative technology.
Orchestra Software Development Kit
Directly access SIGNA PET/MR with QuantWorks’ image reconstruction environment offline and work with raw image data without having to be at the scanner.
PET ToolBox
Develop novel PET imaging techniques using our software tools to access the PET image reconstruction environment.
Organ-Specific Applications
Segment, measure and compare volumetric brain images to normal brain images with NeuroQuant MR for objective support when identifying neurodegenerative diseases.
Analyze brain studies with beta amyloid and FDG tracers and compare them to FDG normals with CortexID multimodality package.
Get a comprehensive cardiovascular assessment with ViosWorks in one free-breathing, eight-minute scan that provides quantitative 3D information for cardiac anatomy, function and flow.
In-vivo Laboratory
Simultaneously use PET/MR with MR multinuclear spectroscopy as an in-vivo laboratory to study fast biochemical processes.
Supporting Materials
SIGNA™ PET/MR with QuantWorks brochure
DISCLAIMER
- MotionFree Brain is 510(k) pending with the US FDA. Not yet CE marked. Not available for sale.
JB00755AU January 2022