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Chemistry Systems

True discovery is made possible because of the biochemical processes that tracers allow us to see. As a result, the research and development of new tracers is just as important as innovations in the technology used to image them. This requires a commitment not only to the efficient production of important tracers like FDG, but also to the development of new tracers that will lead to new avenues of true discovery.

With over 20 years of expertise in PET diagnostic drug development and production as our guide, we developed a portfolio of chemistry systems designed to be highly productive and reliable for your everyday tracer needs, as well as customizable and flexible for your research needs.

FASTlab™ 2 is a multi-tracer platform featuring an innovative, cassette-based design that gives it a unique, plug-and-play functionality. This one-of-a-kind design improves usability, increases efficiency and is economical for wide-spread tracer distribution. In fact, this platform is so innovative and flexible, it’s our platform of choice for developing and producing our own proprietary PET tracers.

For facilities interested in developing novel tracers, the TRACERlab™ FX2 Series of chemistry systems provide the customizable functionality needed to explore different chemistry pathways that require manual manipulations.

With this comprehensive collection of chemistry systems, you can efficiently produce the tracers necessary for true discovery today, or research future tracers that will be needed for tomorrow.

What sets FASTlab 2 apart from all other chemistry systems is its unique, cassette-based design. Pre-measured quantities of every chemical and component needed for the synthesis of a radiopharmaceutical are contained in a single cassette. That means it only takes two simple steps to start producing virtually any clinical tracer you need. All you have to do is drop in a pre-loaded cassette and the system is ready for processing.

This unique, cassette-based system not only simplifies this step of tracer production, it also makes it more reliable and secure compared to other methods. Our cassettes are manufactured in a controlled environment, pre-loaded with reagents produced under cGMP standards, barcoded for automatic identification and sealed shut. They are also disposable, so when a run is complete, each component that comes into contact with the chemical is replaced to ensure clean operation.

FASTlab 2 is designed for easy, confident production of a broad spectrum of PET tracers. It enables automated synthesis of FDG and other 18F-based PET tracers with high output and uptime. Two synthesizers can be stacked into a single hot cell, giving you greater output and saving valuable lab space. With our FDG Duo cassette, you can perform up to four FDG citrate runs without opening the hot cell door. In addition, FASTlab 2 Developer gives you even greater flexibility by enabling you to develop your own tracers and then allowing you to produce them using the cassette system.

 

EASILY ACCOMODATE YOUR DAILY PRODUCTION NEEDS

product-product-categories-pet-radiopharmacy-singular chemistry-icon1.pngStreamline tracer production with a back-to-back synthesis setup that’s as easy as swapping out a used cassette with a new one

product-product-categories-pet-radiopharmacy-singular chemistry-icon2.pngConfidently support all of your daily tracer needs

product-product-categories-pet-radiopharmacy-singular cyclotron-cyclotron image 11.pngIncrease your daily production capacity with consistently high yields and shorter synthesis times that result in more doses per run

product-product-categories-pet-radiopharmacy-singular chemistry-icon4.pngEasily accommodate new tracers as they are developed

Minimal configuration with integrated technologies takes up the least amount of space possible
Minimal configuration with integrated technologies takes up the least amount of space possible
Meet current and future demands with a scalable solution.

FASTlab 2 has three levels of licensing, enabling you to access new tracers* and meet variable demands.


*Customers should gain US Food and Drug Administration (FDA) approval for their tracers. FDA approval has been given for FDG and NaF tracers. Outside US approval depends on local regulation. FMISO, FLT, FDOPA, FET and FES are investigational agents not yet approved by regulatory authorities. FDG Duo cassettes only run on the FASTlab 2 platform. All other GE Multi-Tracer cassettes run on both FASTlab and FASTlab 2 platforms. FDOPA, FET and FES tracer applications are offered by third party-vendors. GE has no liability for third-party products. GE is not responsible for the availability of these tracer applications. †Yield independent of starting activity. Tested up to 25 Ci. Data from FDG citrate and FDG phosphate cassette runs on FASTlab FDG: fluorodeoxyglucose; FLT: fluorothymidine; FMISO: fluromisonidazole; GMP: good manufacturing practices; NaF: sodium fluoride.

A complete tracer solution includes the tools to explore new tracers along with the tools to efficiently produce them. TRACERlab FX2 is a series of advanced synthesis modules that address the challenges of research institutions and hospitals looking to develop novel tracers.

This complete series of customizable synthesizers enable the production of virtually all PET tracers requested by physicians and researchers. It gives you access to each of the major chemistry pathways, including both integrated and scalable 11C tracer synthesis, as well as 18F tracer synthesis through nucleophilic and electrophilic pathways.

Each module is programmable and features a built-in synthesis method editor, so you can easily modify sequences, methods and visual displays with just a few keystrokes. In addition, features like batch report, synthesis log file, trending of critical process parameters and three levels of user permissions support GMP compliance for clinical trial studies and routine production.

STREAMLINE TRACER DEVELOPMENT

product-product-categories-pet-radiopharmacy-singular cyclotron-cyclotron image 11.pngIncrease your production of 11C-based tracers using one TRACERlab FX2 Mel synthesizer to feed up to four TRACERlab FX2 M modules

product-product-categories-molecular-imaging-discovery mi dr-image5.pngSimplify 11C-based tracer production with TRACERlab FX2 C, an automated module that integrates every step of production in one platform

product-product-categories-pet-radiopharmacy-singular chemistry-icon6.pngOptimize production of 18F-based tracers with the fully automated TRACERlab FX2 N synthesizer


Minimal configuration with integrated technologies takes up the least amount of space possible
Minimal configuration with integrated technologies takes up the least amount of space possible

Increase your production of 11C-based tracers using one TRACERlab FX2 Mel synthesizer to feed up to four TRACERlab FX2 M modules
Increase your production of 11C-based tracers using one TRACERlab FX2 Mel synthesizer to feed up to four TRACERlab FX2 M modules

Simplify 11C-based tracer production with TRACERlab FX2 C, an automated module that integrates every step of production in one platform
Simplify 11C-based tracer production with TRACERlab FX2 C, an automated module that integrates every step of production in one platform
Simplify 11C-based tracer production with TRACERlab FX2 C, an automated module that integrates every step of production in one platform

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