DaTQUANT™ Software for Your PC

DaTQUANT™ Software for Your PC

A quantitative analysis of dopamine transporter (DaT) SPECT images now at your fingertips.

An aid in the assessment of the degree of in vivo expression of the dopamine transporter (DaT)

• DaTQUANT assists in the detection and quantification of the loss of functional striatal dopaminergic neuron terminals, a loss correlated with Parkinson’s disease
• Quantitative analysis may help assess the extent and intensity of the striatal 123I-ioflupane signal


Quantification results are indicated for left and right striatal binding ratios, putamen/caudate ratios, and absolute left/right asymmetry. Values are for illustrative purposes only.

Automated processing ensures objective, accurate, and reproducible results

• Uses a predefined 123I-ioflupane VOI template for automatic measurements putamen/caudate update ratios
    -Offers the option for manual adjustment of VOI placement
    -95% of more than 200 images tested required no user intervention for VOI placement
• Reduces variation in comparison to normal database by reconstructing SPECT data with same parameters applied to normal database
• Orients the image automatically for optimal visual assessment and removal of head-tilt artifacts

A normal database developed from healthy volunteers who contributed to the Parkinson’s Progression Markers Initiative, a comprehensive study of patients with Parkinson’s disease2

• In less than one minute, generates quantification results including comparison to age-matched normal volunteers 
• Normal database has been validated for use with images acquired on a variety of multiheaded SPECT cameras
• Users have the ability to create a customized normal database that enables comparison to a site-specific normal population of images

DaT, dopamine transporter; SBR, striatal binding ratio; VOI, volume of interest; SPECT, single-photon emission computed tomography; PDF, portable document format; DICOM, Digital Imaging and Communications in Medicine; PACS, picture archiving and communication system

References:
    1. Internal verification testing data on file. GE Healthcare; 2015.
    2. Parkinson’s Progression Markers Initiative. PPMI-info.org. Accessed 2018.

Indication

Medical Device Indication

The DaTQUANT Software application enables visual evaluation and quantification of 123I-ioflupane (DaTscan) images. DaTQUANT normal database enables quantification relative to normal population databases of 123I-ioflupane (DaTscan) images.

This application may assist in detection of loss of functional dopaminergic neuron terminals in the striatum, which is correlated with Parkinson’s disease.

New Features

New to the DaTQUANT platform

Longitudinal image analysis to aid in the assessment of disease progression

  • Enables access to both a visual and a quantitative comparison of one patient’s images at two separate time points

A comprehensive report of dopaminergic transporter density for your referring physicians

  • Automatically generates a comprehensive PDF report that combines both visualization and quantification reports 
       - Application screens can be saved as DICOM® screen captures and uploaded to a PACS
  • Customizable visual and statistical analyses (options of images, update ratios, and/or visually plotted comparison to normal database)

DaTQUANT Software for your PC offers expanded accessibility and reading flexibility

  • Now available in a stand-alone, PC-based version
  • Expanded normal database derived from the comprehensive Parkinson’s Progression Markers Initiative
  • Automatic processing to enable object, accurate, and repeatable results
  • Longitudinal analysis to enable comparison of one patient’s images over time

PDF, portable document format; DICOM, Digital Imaging and Communications in Medicine; PACS, picture archiving and communication system; PC, personal computer.

System Requirements

    • Minimum 4GB RAM
    • 60GB hard drive (only 250 MB free space is needed)
    • Windows 7,8, or 8.1 (32 or 64-bit versions supported)
    • Minimum monitor resolution of 1024x768 true color (24-bit depth)
    • Easy self-installation (high-speed Internet connection required)

    Contact and Help

    For ordering and billing questions, please call Customer Service at 800 292 8514

    For clinical questions related to DaTQUANT, you can reach Medical Affairs at 800 654 0118 (option 2, then option 3)

    For technical support installing or running the DaTQUANT Software, please call Technical Support at 800 437 1171

    Demo Videos

    Abnormal Patient Processed from Transaxial Slices

    This is an example for processing a patient image with DaTQUANT.

    Performing a Comparative Quantitative Analysis

    This is a demonstration of how to use DaTQUANT to process two studies from the same subject to compare the quantitative analysis.

    Creating a Normal Patient Database

    This video is an example of how to create a normal database with DaTQUANT. DaTQUANT for windows allows user to create their own normal databases of images if they so choose. The images used to creat the normal database can be inputted just as any other image type in DaTQUANT.

    Normal Patient Processed from Raw Data

    This is a demonstration of how a DaT SPECT image is reprocessed within DaTQUANT. DaTQUANT for windows will accept input either as images that are raw topomographic projections acquired by the gamma camera, reconstructed transaxial slices or a previous DaTQUANT results series.

    New Features

    New to the DaTQUANT platform

    Longitudinal image analysis to aid in the assessment of disease progression

    • Enables access to both a visual and a quantitative comparison of one patient’s images at two separate time points

    A comprehensive report of dopaminergic transporter density for your referring physicians

    • Automatically generates a comprehensive PDF report that combines both visualization and quantification reports 
         - Application screens can be saved as DICOM® screen captures and uploaded to a PACS
    • Customizable visual and statistical analyses (options of images, update ratios, and/or visually plotted comparison to normal database)

    DaTQUANT Software for your PC offers expanded accessibility and reading flexibility

    • Now available in a stand-alone, PC-based version
    • Expanded normal database derived from the comprehensive Parkinson’s Progression Markers Initiative
    • Automatic processing to enable object, accurate, and repeatable results
    • Longitudinal analysis to enable comparison of one patient’s images over time

    PDF, portable document format; DICOM, Digital Imaging and Communications in Medicine; PACS, picture archiving and communication system; PC, personal computer.

    System Requirements

      • Minimum 4GB RAM
      • 60GB hard drive (only 250 MB free space is needed)
      • Windows 7,8, or 8.1 (32 or 64-bit versions supported)
      • Minimum monitor resolution of 1024x768 true color (24-bit depth)
      • Easy self-installation (high-speed Internet connection required)

      Contact and Help

      For ordering and billing questions, please call Customer Service at 800 292 8514

      For clinical questions related to DaTQUANT, you can reach Medical Affairs at 800 654 0118 (option 2, then option 3)

      For technical support installing or running the DaTQUANT Software, please call Technical Support at 800 437 1171

      Demo Videos

      Abnormal Patient Processed from Transaxial Slices

      This is an example for processing a patient image with DaTQUANT.

      Performing a Comparative Quantitative Analysis

      This is a demonstration of how to use DaTQUANT to process two studies from the same subject to compare the quantitative analysis.

      Creating a Normal Patient Database

      This video is an example of how to create a normal database with DaTQUANT. DaTQUANT for windows allows user to create their own normal databases of images if they so choose. The images used to creat the normal database can be inputted just as any other image type in DaTQUANT.

      Normal Patient Processed from Raw Data

      This is a demonstration of how a DaT SPECT image is reprocessed within DaTQUANT. DaTQUANT for windows will accept input either as images that are raw topomographic projections acquired by the gamma camera, reconstructed transaxial slices or a previous DaTQUANT results series.