TRACERlab FX C Pro

TRACERlab™ FX C Pro is an automated versatile synthesizer for easy and efficient production of [11C] labeled tracers. It facilitates methylation reactions using methyl iodide or methyl triflate produced from either carbon dioxide or methane.

Purification is achieved by a integrated preparative HPLC system. Through the application software, all process steps are easily programmed to produce the required tracers.

Now available: Upgrade for TRACERlab FX C to TRACERlab FX C Pro

  • More yield
  • Higher specific activity
  • Less operator intervention
  • Direct carboxylation with CO2


Features

  • 3 reagent vials
  • 3 formulation vials
  • 2 high temperature ovens for gas phase reactions
  • 2 molecular sieve traps, can be heated and cooled
  • Cryogenic 11C-methane trap
  • Electronic mass flow controller for incoming gases
  • Gas recycling pump
  • 1 glass reactor (small) with magnetic stirrer and retractable needle
  • 5 Geiger-Müller counters
  • Sub-zero cooling of reactor (liquid N2)
  • Vacuum system with cryogenic trap
  • Purification with preparative HPLC
    • 2 HPLC eluents
    • HPLC flow control
    • Automatic loop filling with fluid detector
    • UV and radioactivity HPLC detector
  • Fraction collection and dilution vessel
  • Solid phase extraction (SPE) HPLC solvent removal
  • Formulation of final tracer


Examples of [11C] Compounds
Tracer Molecular Level Disease Level
11C Raclopride Dopamine post synaptic receptors Psychiatry
11C Metahydroxyephedrine Adrenergic neurotransmission Cardiology
11C Methylspiperone Dopamine post synaptic receptors Psychiatry
11C Methionine Protein synthesis Oncology
11C Acetate Cell metabolism Cardiology
11C Palmitate Fatty acid metabolism Cardiology