eXplore Locus SP

eXplore Locus SP

Detecting, characterizing and quantifying anatomical changes in small tissue specimens require high resolution and superior image quality. Unlike histopathology approaches, pre-clinical micro CT provides continuous, 3-dimensional visualization and analysis of the entire specimen volume, providing extraordinary resolution in a non-destructive manner.

The eXplore Locus SP from GE Healthcare is an ex-vivo pre-clinical specimen scanner optimized for visualizing and analyzing extremely small structures. Using cone beam technology, eXplore Locus SP acquires the entire sample volume in a single scan achieving isotropic resolutions at 8µm.

Features

 
Features  
  • 50-90 kV adjustable source voltage
  • 5 selectable x-ray filters
  • Temperature-stabilized CCD detector
  • High-performance workstation
  • MicroView™ viewing & analysis software
  • Optimized bone analysis application software
 
 
 

Benefits

 

   
Benefits  
  • High-resolution: < 8um - 100um isotropic
  • Large diameter samples, up to 44mm diameter
  • Large acquisition volume, up to 56mm high
  • High precision specimen rotate design
  • Calibrated image data in HU for quantitative analysis
 
     
 

Applications
     
Applications
   Bone Disease: assess disease development through volumetric bone density measurements, subchondral micro-architectural parameters and anatomical changes

Oncology: differentiate normal tissues from tumors through analysis of angiogenic parameters

Implants: assess mineralization in dental and orthopedic applications

Phenotyping: characterize anatomical differences in tissue, organ, vascular, and skeletal formation in normal or transgenic models
Applications
 		  Cardiovascular disease: image stenosis, vascular disease and development, injury/repair, vessel geometry and the effects of therapy