eXplore Locus

eXplore Locus

Due to significant advances in transgenic and animal models of disease, new challenges emerge to effectively and efficiently obtain accurate, quantitative data in a non-invasive manner.

The eXplore Locus in vivo MicroCT scanner from GE Healthcare overcomes these challenges and delivers high quality volumetric images with low dosing to support the most demanding longitudinal studies.

With an intuitive user interface and a comprehensive list of visualization and quantification software features, the eXplore Locus provides an optimal solution for a broad range of pre-clinical imaging research applications.

Features

 
Features  
  • Variable resolution: 27, 45, 90mm isotropic
  • Large FOV (mouse and rat): up to 80mm
  • Low dose, rapid large area scanning for in-vivo applications
  • High precision rotate gantry system
  • Large area volumetric acquisition
  • Calibrated image data in Hounsfield Units (HU) for quantitative analysis
 
 
 

Benefits

 

   
Benefits  
  • Superior image quality for accurate and repeatable quantification and visualization
  • Easy-to-use software and hardware to support diverse applications
  • Anatomical and functional co-registration to support multi-modality imaging
  • Streamlined workflow for maximum throughput and efficient data management
  • Inputs for respiratory gating
  • Compatibility throughout the eXplore series of imaging systems for seamless PET and SPECT co-registration
 
     
 

Applications

     
Applications
  Bone Disease: assess disease development through volumetric bone density measurements, cortical bone parameters and anatomical changes

Oncology: differentiate normal tissues from tumors through analysis of angiogenic parameters, measure solid tumor volumes, and quantify metastases

Respiratory disease: visualize and quantify airway structures and vasculature of the lungs, measurement of bronchial thickness

Applications
  Cardiovascular disease: image stenosis, vascular disease and development, injury/repair, vessel geometry and the effects of therapy

Phenotyping: characterize anatomical differences in tissue, organ, vascular, and skeletal formation in normal or transgenic models