eXplore CT 120

eXplore CT 120

The eXplore CT 120 pre-clinical x-ray CT scanner is a performance high-throughput small animal scanner designed for high quality scanning for the widest variety of applications. It is designed to visualize, quantify, and characterize anatomical parameters in small animals such as mice and rats. Its table design, versatile bed mount and built-in software support allows image registration with other imaging modalities.

The all-new hardware and software of the eXplore series of scanners achieves 2-4x the throughput of traditional micro-CT systems.

The CT 120 can perform prospectively-gated respiratory and cardiac imaging with extremely high precision, to reduce motion artifacts in the heart and thorax. The system includes shielded ports for ventilation tubing, anesthetic gases, or monitoring hardware.

Features

 
Features  
  • Rapid scans facilitated by a 5 kW pulsed high-output x-ray tube
  • Application flexibility enabled by adjustable imaging parameters: Tube potential 70-120 kV, current up to 50 mA, exposure time as short as 8 ms
  • Rodent cardiac imaging made possible by less than 1 millisecond pulse precision, capable of capturing over 600 beats per minute
  • Multi-modality support built-in for hybrid imaging
  • X-ray filtering reduces animal dose, decreases image artifacts
Image courtesy of
Dr. P. Choquet Hôpital de Hautepierre, Strasbourg, France
 
 
 

Benefits

 

   
Benefits  
  • High performance, high throughput CT
  • Large 3D volume imaging
  • Optimized for mouse and rat imaging
  • Low dose ECG-gated cardiac imaging
  • Respiratory-gated imaging
  • High quality, low-artifact images
  • Excellent soft tissue contrast
  • Low bone artifacts
  • Compatibility throughout the eXplore series of imaging systems for seamless PET and SPECT co-registration
   
     
 

Applications

     
Applications
Cardiovascular disease: image stenosis, vascular disease and development, injury/repair, vessel geometry and the effects of therapy

Cardiac imaging: quantify wall thickness, ventricular volume, ejection fraction, and cardiac output

Respiratory disease: visualize and quantify airway structures and vasculature of the lungs, measurement of bronchial thickness

Phenotyping: characterize anatomical differences in tissue, organ, vascular, and skeletal formation in normal or transgenic models

Oncology: differentiate normal tissues from tumors through analysis of angiogenic parameters, measure solid tumor volumes, and quantify metastases

Body composition: contrast segmentation of soft tissue from fat to perform fat analysis

Bone disease: assess disease development through volumetric bone density measurements, cortical bone parameters and anatomical changes

Applications Images courtesy of Timothy Doyle, Stanford Small Animal Imaging Facility