PET Advance - Alveolar Soft-part Sarcoma

General Information:
A 34 year old male presented with a history of recently diagnosed alveolar soft part sarcoma of the right thigh. The PET study was performed as part of an initial staging work-up and to help elucidate CT findings. A CT scan of the chest, performed two weeks prior to the PET study, demonstrated diffuse miliary metastases of both lungs as well as 1 cm pretracheal and subcarinal soft tissue masses in the mediastinum suspicious for metastatic disease.

Imaging Procedure:
One hour after the injection of 662 MBq of FDG, sequential PET images from the ear to the knee were obtained with the GE Advance (7 minute emission, 3 minute transmission per bed position). Data were reconstructed using an OSEM algorithm and segmented attenuation correction.

 
Findings:
The PET study demonstrated increased metabolic activity in the area of the primary thigh sarcoma as well as extensive and highly metabolic uptake in the mediastinum as well as the lower lobes of both lungs.

Comments: Lung Metastases and Soft Part Sarcoma
Alveolar soft-part sarcoma is a rare soft tissue sarcoma which frequently spreads to the lung. Surgical excision of lung metastases is the well accepted treatment option of choice. However, when complete resection can not be achieved, other treatment options or palliative measures are usually considered.

References:
Chao C, Goldberg M
Surgical treatment of metastatic pulmonary soft-tissue sarcoma.
Oncology (Huntingt) (United States), Jun 2000, 14(6)
p835-41; discussion 842-4, 847

Choi JI, Goo JM, Seo JB, et al.
Pulmonary metastases of alveolar soft-part sarcoma: CT
findings in three patients.
Korean J Radiol (Korea), Jan-Mar 2000, 1(1) p56-9

Images courtesy of Lake Hospital Systems, Willoughby OH
and NEO-PET, LLC, Oakwood, OH

 
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