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Lymphoma Case Study
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Patient History:
59-year-old male, with a history of large B cell, non-Hodgkin’s lymphoma at base line.
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Imaging Procedure:
Whole body transmission/emission tomography was formed 90 minutes after the injection of 9 mCi F-18 FDG.
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Findings:
CT showed lymphadenopathy above and below the diaphragm and a lesion in L-3 vertebra consistent with a compressed or pathological fracture. The final diagnosis of lymphoma was made after biopsy of enlarged right inguinal lymph nodes and by bone marrow biopsy. There are areas of increased pathological activity in the left supra and infraclavicular region, the upper and mid-mediastinum, the right pulmonary hilus, D-8, D-12, L-2, L-3, L-4 vertebrae and the left inguinal region.
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Clinical Impact – The FAM Advantage
The combined study allowed for precise localization of involvement of thoracic and lumbar vertebrae in addition to paravertebral soft tissue involvement. It also allowed for the differential diagnosis of areas of increased activity in the anterior abdomen, which appear to be in the bowel due to physiologic intestinal excretion of FDG. Bone scintigraphy and follow-up CT confirmed all sites of disease seen on the combined Functional Anatomical Mapping study.
Images Courtesy of:
Vanderbilt University
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