LightSpeed™ VCT

Coronary CTA Using SnapShot Pulse to Evaluate Etio

Coronary CTA Using SnapShot Pulse to Evaluate Etiology of Chest Pain

James Earls, M.D. Fairfax Radiological Consultants, PC. Fairfax, Virginia

Patient history

Clinical findings

A 65-year-old female patient came in for a work up due to complaints of atypical chest pain which radiated to her back. Although she had numerous cardiac risk factors, she had no previous cardiac history. This patient is obese with a BMI > 37. Body mass index (BMI) is a measure of body fat based on height and weight that applies to both adult men and women.


BMI categories

  • Underweight: <18.5
  • Normal weight: 18.5-24.9
  • Overweight: 25-29.9
  • Obesity: BMI ³ 30


The patient’s cardiac risk factors include a history of high cholesterol, positive family history, hypertension and insulin-dependent diabetes. Her calcium score of 101 is broken down as follows:

  • Left main: 0
  • Left anterior descending: 85
  • Left circumflex: 0
  • Right coronary: 16
  • Posterior descending: 0
  • Total calcium score: 101
  • Age/sex matching score percentile: 80


Patient physiological data

  • Average HR: 45 bpm
  • Height: 5' 5''
  • Weight: 225 lbs
  • BMI 37.4


Acquisition protocol

  • Scanner: LightSpeed® VCT XT
  • Scan type: Cardiac SnapShot™ Pulse
  • Rotation speed: 0.35 second
  • Detector configuration: 64 x 0.625 mm
  • Slice thickness: 0.625 mm
  • kVp: 120
  • mA: 750
  • Total X-ray exposure time: 1.0 second
  • Total scan time: 5 seconds
  • Total radiation dose: 2.33 mSv*


Contrast injection parameters

Visipaque™ contrast injection parameters:

  • Timing dose: 20 cc at 5.5 cc/second followed by 50 cc saline at 5.5 cc/second
  • Diagnostic dose: 80 cc at 5.5 cc/second followed by 50 cc saline at 5.5 cc/second


Diagnosis

Clinical findings

The left main coronary artery is patent with evidence of mild atherosclerosis (Figure 1).

The left anterior descending (LAD) and diagonals are patent although there is evidence of mild nonobstructing atherosclerosis (Figure 1).

The left circumflex coronary artery (LCx) and marginal branches are patent. Again, there is evidence of mild nonobstructing atherosclerosis.

The right coronary artery (RCA) is a very prominent vessel (Figure 2, a and b). It has a maximum diameter of 7.0 mm proximally (b). This is seen over the proximal several centimeters of the vessel. Several small plaques are identified throughout the nonobstructed vessel.

The posterior descending artery (PDA) arises from the right coronary artery. The vessel is patent without obstruction (Figure 3).

Based on the findings, the patient has mild atherosclerosis seen in her LAD, LCx and RCA. She has a very prominent proximal right coronary artery with a widely patent PDA. The atherosclerosis, while being mild in nature, will warrant observation in the coming years for further progression.


Discussion

The benefits of SnapShot Pulse on the LightSpeed VCT XT are demonstrated with this large BMI study. We are now able to provide diagnostic quality coronary CT images with substantially reduced radiation exposure to the patient as compared to helical techniques.

Currently in clinical practice, patients with known coronary artery disease are frequently followed with serial nuclear myocardial perfusion imaging (MPI) studies. These can have radiation doses to the patient that, in the case of thallium MPI studies, approach 50 mSv per study. In addition, women and obese patients have a higher incidence of false-positive MPI studies due to breast or diaphragmatic attenuation, often obligating that a diagnostic invasive coronary catheterization be performed.

This new low-dose coronary CTA technique provides the clinician with new possibilities for following a patient’s disease process because of the lower dose exposure.


* Obtained by EUR-16262 EN using chest factor of 0.017*DLP