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Assessing In-stent Restenosis Using VesselIQ Xpress
CT Clinical Case Study
CT Angiography
James P. Earls, M.D.
Vice President & Medical Director
Fairfax Radiological Consultants
Fairfax, Virginia
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A 71-year-old female has a history of peripheral vascular
disease, coronary artery disease, hypertension and
hyperlipidemia. This patient has undergone numerous
cardiac and peripheral procedures in the past. On a previous
occasion, an 8 x 40 Smart Stent was placed in the right
external iliac artery, and a 7 x 40 Smart Stent was placed in
the proximal right superficial femoral artery.
Acquisition protocol
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Scanner: GE Healthcare LightSpeed® VCT
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Scan type: CT abdomen/aorta with
peripheral runoff
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Helical
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kVp: 120
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mA: 170
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Noise index: 12.0
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Rotation speed: 0.60 second
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mAs: 102
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Slice thickness: 1.25 mm
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Collimation: 40 mm (64 x 0.625 mm)
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Pitch: 0.984:1
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SFOV: 50 cm
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Contrast injection parameters
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Total contrast volume: 150 cc
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Contrast injection rate: 5.0 cc/second
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Clinical findings
The CTA exam images helped the radiologist determine
the following: Moderate to possibly greater in-stent
restenosis of the right external iliac and right superficial
femoral artery stents. Severe focal stenosis in the right
common femoral artery. Moderate stenosis of the distal
superficial femoral artery on the right. Probable occlusion of
the left superficial femoral artery with multiple collateral
vessels. Focal aneurysm of the proximal left superficial
femoral artery measuring 2.4 x 2.6 cm in diameter and
4.1 cm in length.
Significant disease of the superficial femoral artery on the
left. Collateral flow is provided by the profunda femoris
artery and muscular collaterals to the level of the distal
superficial femoral artery.
There is a second aneurysm of the left superficial femoral
artery measuring 4.1 cm in length by 2.1 x 2.2 cm in
diameter. This appears to be predominately thrombosed.
Distal to this there is adequate three-vessel runoff to the left
ankle. There is a mild stenosis at the origin of the anterior
tibial artery.
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The improved acquisition speed and temporal resolution of
the LightSpeed VCT system using VesselIQ Xpress has
improved our capabilities for imaging the peripheral vascular
system over our single-slice, 4-slice and 16-slice systems.
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The depiction of the plaque accumulation within the two
stents depicted in this case is, in my opinion, outstanding
and was very useful in making a complete and accurate
diagnosis in this case.
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The new VesselIQ Xpress software was of great help in
assessing this case. The ability to use curved planar
reformations to evaluate the vessel lumen is a significant
advance over earlier versions of the software. As we know
from using curved planar reformations to evaluate the
coronary arteries, we are now able to view the entire vessel
lumen and wall in 360 degrees of rotation for each vessel.
This enabled us to determine the presence, shape, and
degree of luminal encroachment of even small plaques.
As demonstrated here, we now have a powerful tool for
assessing intravascular stents. In addition, when trying to
make a diagnosis within the small infrapopliteal arteries,
VesselIQ Xpress truly shines, decreasing the time a physician
must spend to make a diagnosis as well as substantially
improving the physician’s degree of confidence in that
diagnosis.
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